Lexicon

SPPD - 'Split Paw Pad Disease' refers to a hereditary disease of the paw pads that occurs in dogs and results in lesions of varying severity and cause. A mutation has been isolated in a specific lineage of the German Shepherd breed that causes the symptoms in the affected animals. 
The genetic test can be used to identify unclear cases and asymptomatic carriers.

Squamous cell carcinoma (SCC) is a malignant tissue formation (tumor) originating from the superficial layers of the skin and mucous membranes. It is the most common type of eye cancer in horses. This test identifies a gene mutation that increases the risk of developing SCC.

This mutation for SCC has been found in Haflingers and Percherons. The inheritance is autosomal recessive.

Genetic Test: available in Shop

Stargardt disease (STGD) is an eye disease in which affected dogs show impaired vision. Due to a mutation in the gene for a membrane transporter protein in the photoreceptor cells (cones and rods), lipofuscin ("age pigment") is deposited in the retinal pigment epithelium (RPE) of the retina and the photoreceptor cells slowly degenerate.

The disease occurs in the Labrador Retriever and the inheritance is autosomal recessive.

Synonym: STGD-PRA, Morbus Stargardt

Genetic Test: available in Shop

Stumpy tail (Bobtail - Brachyuria) is a natural form of shortened tail in dogs. The trait occurs in some breeds: Welsh Corgi Pembroke, Australian Shepherd, Jack Russell Terrier, etc..

This trait is homozygous lethal. Dogs with two copies of the mutated gene die before birth.

The Sunshine mutation lightens the coat, mane and tail colour of the horse. It is visually very similar to the Pearl dilution and is located on the same gene as the Cream dilution factor. It was found in a horse of the cross breed Standardbred x Tennessee Walking Horse.

The Tobiano pattern is characterised by large white patches with defined edges or sometimes with a lighter pigmented fringe. Often the head is coloured and white patches extend over the back to the other side.

The pattern is occurs in many breeds and is probably the most common.

Genetic Test: available in Shop

Von Willebrand disease type 1 (VWD1) is a blood coagulation disorder. The Von Willebrand factor plays an important role in blood clotting. If the disease occurs, there is a deficiency of this factor or it is dysfunctional, which causes the affected animals to show symptoms such as intensive and persistent bleeding when injured (e.g. also after operations).

The disease (type 1) occurs in the Doberman. The inheritance is autosomal recessive.

Genetic Test: available in Shop

Also in the Doberman 1 package

Warmblood Fragile Foal Syndrome (WFFS) is a connective tissue disorder in warmbloods that leads to skin detachment. Affected foals die or have to be euthanized. The disease is inherited in an autosomal recessive manner.

Synonym: Ehlers-Danlos syndrome VI

Genetic Test: available in Shop

White Spotting (previously called 'Dominant White') is a general name given to a large number of white spotting patterns caused by mutations in the KIT gene. 30 'W' mutations are currently known. There is a large amount of variability in the amount/pattern of white caused by each of the mutations (W1-W30). Most 'W' mutations are breed or line specific, having originated in one specific horse.

Genetic Test: available in the Shop (W8, W19, W20, W21, W30)

Please ask us for more tests!

The dog shows the typical "wolf-grey" colour all over the body. This colouration is caused by the aw allele of the Agouti locus.

See: Agouti (Fellfarbe A-Lokus Hund)