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Malignant Hyperthermia (MH Dog)

Malignant Hyperthermia (MH) is also known as "Canine Stress Syndrome (CSS)". Affected animals exhibit symptoms such as high fever, muscle cramps/stiffness, or respiratory distress. Some affected animals appear healthy, but exhibit the above symptoms under stress.

The disease occurs in many breeds. The inheritance is autosomal dominant. It occurs when one or both copies of the gene (n/MH or MH/MH) are affected by the mutation.

 

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Malignant Hyperthermia (MH Horse)

Malignant hyperthermia (MH) causes anesthesia- or stress-induced muscle rigidity with fever and respiratory distress. MH results in death of the horse in approximately 34% of cases.

The disease occurs in many breeds. The inheritance is autosomal dominant.

 

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Melanistic Mask (Coat colour E-Locus Dog)

The dog has black markings over the muzzle and face ("mask"). This colour pattern is caused by the Em allele of the extension locus.

 

See: Extension (Coat colour E-Locus Dog)

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Merle (Coat colour M-Locus Dog)

Merle coloured dogs show a pattern of darker and lighter patches which appears random. The eyes may be lighter or blue in colour.

The colour is caused by the M allele of the M locus. Homozygous animals (M/M) have severe health problems such as deafness, blindness and organ problems.

 

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Mushroom (Dilution factor Horse)

Mushroom is a coat colour unique to the Shetland Pony, where phaeomelanin (chestnut colour) is lightened to a light sepia shade. Mushroom can also slightly affect the coat colour of ponies with bay base colour.

The colour is inherited autosomal recessively. Animals with one copy of the mutation (N/mu) show no dilution. Only animals with two copies of the mutation (mu/mu) show the Mushroom dilution.

 

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