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Nutrition has the greatest influence on the management of symptoms in a horse with Muscle Integrity Myopathy (PSSM2).  Most horses with one or more variants profit from high protein in the diet along with supplementation of specific nutrients.


Of great importance:

  • High protein diet*

  • Supplementation of essential amino acids (lysine, methionine, threonine)

  • High quality hay

  • Oil as a source of fat and calories


Can be helpful:

  • Vitamin E

  • Magnesium

  • Manganese

  • Reduced sugar and carbohydrates


*There is some evidence that horses with K1 benefit from a reduced-protein diet based on work in human patients with COL6 myopathies.


Please note that the change of feeding in horses with Muscle Integrity Myopathy is extremely important and must be properly balanced. We recommend consultation with a veterinarian or nutritionist. If the horse’s health is already compromised by another condition, this should be discussed with the veterinarian treating the animal to avoid any effect on the existing problem.

If you do not already have a nutrition consultant, generatio offers a science-based, brand-independent consultation service through our qualified equine nutrition consultant.


Before making a change in feeding, we recommend having blood work done to make sure that the horse is otherwise healthy, and to ensure that the trace elements in the diet (especially selenium) are within normal parameters. 


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