Lexicon

Ectodermal dysplasia (ED) is a skin disease in which affected puppies have extremely thin and fragile skin that peels off even when touched lightly. Puppies with this condition are usually euthanised immediately after birth.

The disease occurs in Chesapeake Bay Retrievers. It is inherited in an autosomal recessive manner.

Synonym: Skin fragility syndrome

Exercise-induced collapse (EIC) is a neuromuscular disorder characterised by exercise intolerance in otherwise healthy dogs. The first signs begin within 2 minutes of strenuous exercise. Affected dogs then show a wobbly gait with weakness of the hind legs, coordination difficulties and general weakness. The cause is the malformation of dynamin 1 (DNM1), a neurotransmitter.

The hereditary disease occurs in the Labrador Retriever and other Retriever breeds. The inheritance is autosomal recessive.

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Also in the Labrador Retriever A package (DRC P1)

Three base colours occur in the horse: Chestnut (reddish), Black and Bay (Brown).The base colour is determined by the combination of the Extension locus (E) and Agouti locus (A).

The Extension locus (E) controls the production of the black pigment 'eumelanin' in the melanocytes.

If the gene is altered and non-functional (ee), the black pigment cannot be produced and the horse has a chestnut coat colour. Horses with one or two intact copies of the extension gene (EE, Ee) are either bay or black (depending on the Agouti gene).

Genetic Test: available in Shop

Also in the Base Colour package

The base colour of the dog is determined by the interaction of the the E locus (Extension), A locus (Agouti) and the K locus (BlacK). The alleles of these loci determine if and where the pigment eumelanin (black colour) and the pigment phaeomelanin (red colour) can be produced and how these two are distributed over the body.

The E locus has different alleles which determine whether and where the dark pigment eumelanin can be produced. If eumelanin cannot be produced, the dogs show a light sometimes reddish colouring, because only the red/light pigment phaeomelanin is produced.

Genetic Test: available in Shop