Skip to main content

Lexicon

Pearl (Dilution factor Horse)

The Pearl mutation lightens the coat, mane and tail colour of the horse. It is visually very similar to champagne dilution and is located on the same gene as the cream dilution factor. The Pearl mutation is mainly found in Quarter Horses, Paints and related breeds.

Read more »

Predictive height test (HMGA2 Pony)

Height in animals depends on various factors (e.g. genes, environment and their combination). A genetic variation has been discovered for the height of ponies. A base pair change in the HMGA2 gene can influence/reduce height. This is especially influential in Shetland ponies and related breeds.

In Shetland ponies, this test allows breeders to estimate the height of offspring. Here, the ponies are assigned to three height groups: A/A (Small: ~ 84 cm), A/G (Medium Small: ~ 98 cm) and G/G (Normal: ~ 104 cm). 

The test is also appropriate for other pony and miniature horse breeds.

Read more »

Predictive height test (LCORL Horse)

Height in animals depends on various factors (e.g. genes, environment and their combination). Genetic variation has been discovered for the Height of warmblood horses. A base pair in the LCORL regulatory unit (on the third chromosome) determines to a large extent what height the horse will become.

This test allows breeders to estimate the height of the offspring with an accuracy of 70% (+/- 5 cm). Here, the horses are assigned to three height groups: T/T (Normal height: ~ 159 cm), C/T (Medium height: ~ 164 cm) and C/C (Tall heigth: ~ 169 cm).

This genetic variation has a smaller effect on height in non-warmblood horses.

 

Genetic Test: available in Shop

Read more »

Progressive retinal atrophy type 1 (GR-PRA 1 Golden Retriever)

Progressive retinal atrophy type I (GR-PRA 1) is caused by degeneration of the retinal photoreceptor cells and, in the course of the disease, the entire retina is destroyed. Affected animals go blind.

The hereditary disease is one of the three forms of PRA in the Golden Retriever. The inheritance is autosomal recessive.

 

Genetic Test: available in Shop

Also in the Golden Retriever B package

Read more »

Progressive retinal atrophy type 2 (GR-PRA 2 Golden Retriever)

Progressive retinal atrophy type II (GR-PRA 2) is caused by degeneration of the retinal photoreceptor cells and, in the course of the disease, the entire retina is destroyed. Affected animals go blind.

The hereditary disease is one of the three forms of PRA in the Golden Retriever. The inheritance is autosomal recessive.

 

Genetic Test: available in Shop

Also in the Golden Retriever B package (DRC P4)

Read more »

Progressive rod-cone degeneration (prcd-PRA Dog)

Progressive rod-cone degeneration (prcd-PRA) is caused by degeneration of the retinal photoreceptor cells and, in the course of the disease, the entire retina is destroyed. Affected animals go blind.

The hereditary disease is one of the three forms of PRA in the Golden Retriever, but also occurs in many other breeds. The inheritance is autosomal recessive.

 

Genetic Test: available in Shop

Also in the Labrador Retriever A Paket (DRC P1)

Read more »

PSSM1 (Polysaccharide Storage Myopathy 1 Horse)

Polysaccharide storage myopathy (PSSM1) is a degenerative muscle disease caused by a disorder of sugar metabolism. Affected horses show symptoms such as reluctance to move, muscle tremors and tension.

The disease occurs in many breeds. The inheritance is incomplete autosomal dominant.

 

Genetic Test: available in Shop

Read more »

PSSM2 (Equine Myopathy Horse)

Equine myopathy (PSSM2) is a collective term for a number of related muscle disorders with similar clinical symptoms. Typical symptoms include reluctance to move, intermittent lameness, stiffness, and in daily practice it can manifest as exercise intolerance. Symptoms are generally adult-onset, usually after 7-10 years of age (depending on breed and environment); mild symptoms may be obvious at a younger age or after a "trigger" leading to negative nitrogen balance.

DNA tests are now available for six variants associated with horses developing symptoms of PSSM2.

 

Genetic Test: available in Shop

Read more »

Recessive black (Coat colour A-Locus Dog)

The dog is black all over the body, the hairs are not bicoloured (brown/black) as in the other agouti genes. This colouration is caused by the recessive a allele of the Agouti locus.

 

See: Agouti (Fellfarbe A-Lokus Hund)

Read more »

Sabino-1 (Coat colour pattern Horse)

Horses with the Sabino-1 pattern often have white patches of different sizes with 'indistinct/fringed' borders especially on the head, belly and legs. Many horses have often white ticked hair on the rest of the body (animals with one copy of the gene: Sb1/n). Horses with two copies of the mutation (homozygous) are usually completely white.

 

Sabino-1 is a special form of White Spotting/Dominant White and is the most common, but not the only mutation causing this spotting pattern. Should a horse show a Sabino-like pattern but does not have an Sb1 mutation, other mutations in the KIT gene, the so-called W-variants, could be responsible.

Read more »